Parasitic Flatworms:Molecular Biology, Biochemistry, Immunology and Physiology
Edited by A Maule, Professor of Molecular Parasitology, Queen's University Belfast, UK, N Marks, Queen's University, Belfast, Northern Ireland
Parasitic flatworms include Cestodes (tapeworms) and trematodes (flukes, schistosomes, etc) and are the cause of a number of major diseases of medical and veterinary significance. Much recent research has focused on molecular biology and genomics. this book aims to review advances in our understanding of these and related topics such as flatworm biochemistry, immunology and physiology. Where appropriate, comparisons are made between different parasitic flatworms and between parasitic and free-living species. Contributors to the book include leading authorities from Europe, North and South America, and Australia.
Researchers in parasitology, immunology and infectious diseases.
Part I: Phylogeny, Genetics and TranscriptomesThe Evolution of Parasitism in Flatworms, D T J Littlewood, Natural History Museum, UKGenomes and Genomics of Parasitic Flatworms, D A Johnston, Natural History Museum, UKGenetic Discrimination of Echinococcus Species and Strains, D P McManus, University of Queensland, AustraliaRibosomal DNA Variation in Parasitic Flatworms, D Blair, James Cook University, AustraliaGenetic Studies on Monogeneas with Emphasis on Gyrodactylus, ,CO Cunningham and I Matějusová, FRS MarineLaboratory, Aberdeen, UKThe Schistosome Transcriptome, S Verjovski-Almeida and R DeMarco, Universidade de Sao Paulo, BrazilTransgenic Flatworms, C G Grevelding, Justus-Liebig-University Giessen, GermanyPart II: Immunobiology, Host-Parasite Interaction and ControlImmunobiology of Schistosomes, S G Forrester, University of Ontario, Canada and E J Pearce, University of Pennsylvania, USACestode Infection: Immunological Considerations From Host and Tapeworm Perspectives, D M McKay, McMaster University, and R A Webb, York University, CanadaParasitic Flatworms: Signal Transduction at the Host-Parasite Interface, T P Yoshino, J J Vermeire and J Humphries, University of Wisconsin-Madison, USAParasite Effects on the Snail Host Transcriptome, M Knight and N Raghavan, Biomedical Research Institute, USADevelopments in the chemotherapy of parasitic flatworms, G C Coles, University of Bristol, UKDrug Resistance in Schistosomes, T A Day, Iowa State University, USA and S Botros, Theodor Bilharz Research Institute, EgyptPraziquantel: Mechanism of Action, R M Greenberg, Marine Biological Laboratory, Woods Hole, MA, USACestode Vaccine Development, M W Lightowlers, University of Melbourne, AustraliaThe Development of a Schistosome Vaccine, R A Wilson and P S Coulson, University of York, UKPart III: Protein Function, Metabolism and PhysiologyFlatworm Parasite Proteomics, R M Morphew, J Barrett and P M Brophy, University of Wales, UKProteases in Trematode Biology, J P Dalton, University of Technology, Australia, C R Caffrey, M Sajid, University of California, USA, C Stack, S Donnelly, University of Technology, Australia, A Loukas, T Don, Queensland Institute of Medical Research, J McKerrow, University of California, USA, D W Halton, Queen’s University Belfast, UK and P J Brindley, Tulane University Health Sciences Center, USASignalling Molecules and Nerve-Muscle Function, A G Maule, N J Marks and T A DayUnusual Aspects of Metabolism in Flatworm Parasites, A G M Tielens and J J van Hellemond, Utrecht University, NetherlandsGlycoconjugate Structures, M Wuhrer, Leiden University Medical Center, Netherlands and R Geyer, University of Giessen, GermanyGene Silencing in Flatworms using RNA interference, P J Skelly, TuftsUniversity School of Veterinary Medicine, USA
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