Quantitative Trait Loci Analysis in AnimalsModular Texts
By J Weller, Researcher, Agricultural Research Organization (ARO), Israel
Quantitative Trait Loci (QTL) is a topic of major agricultural significance for efficient livestock production. This advanced-level textbook covers all the statistical methods that have been used or proposed for detection and analysis of QTL and marker- and gene- assisted selection in animal genetics and breeding, as well as new advances that have revolutionized the field since the first edition.
Graduate students and researchers in genetics/genetic markers/quantitative genetics, applied animal breeding, bioinformatics.
1. Principles of Parameter Estimation2. Random and Fixed Effects, the Mixed Model3. Historical Overview4. Experimental Designs to Detect QTL, Generation of Linkage Disequilibrium5. QTL Parameter Estimation for Crosses between Inbred Lines6. Advanced Statistical Methods for QTL Detection and Parameter Estimation7. Analysis of QTL as Random Effects8. Statistical Power to Detect QTL, and Parameter Confidence Intervals9. Optimization of Experimental Designs10. Fine Mapping of QTL11. Complete Genome QTL Scans: The Problem of Multiple Comparisons12. Multiple Trait QTL Analysis13. Principles of Selection Index and Traditional Breeding Programmes14. Marker-assisted Selection:Theory15. Marker-assisted Selection : Results of Simulation Studies16. Marker-assisted Introgression
Animal Science Reviews 2011
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