Lyme Diseasean Evidence-based ApproachAdvances in Molecular and Cellular Microbiology
Edited by J Halperin, Professor of Medicine and Neurology, Mount Sinai School of Medicine, USA
Providing the medical practitioner with a broad scientific understanding, this book discusses the causative organism, its requisite ecosystem, disease epidemiology, host-Borrelia interactions, diagnostic testing, clinical manifestations, therapeutic options, and long term prognosis. It explicitly reviews both the basic biology of the infection and practical clinical aspects, linking the two to demonstrate what is and is not attributable to this infection. It is a broad and detailed guide for medics and researchers involved with diagnosing and treating Lyme, covering biology, epidemiology and therapeutics.
Researchers, students and clinicians in global health and infectious diseases.
Part I: Biological Substrate1. Ticks: the Vectors of Lyme Disease2. Borrelia: Biology of the Organism3. Borrelia: Interactions with the Host Immune System4. Laboratory Diagnostic Testing for Borrelia burgdorferi Infection5. Persistence of Borrelia burgdorferi Infection aft er Antibiotic Treatment: What Can We Learn from Animal Models? 6. Global Epidemiology of Borrelia burgdorferi Infections Part II: Clinical aspects7. Antibiotic Therapy for Infection Caused by Borrelia burgdorferi Sensu Lato 8. Lyme Borreliosis in the UK and Ireland 9. Lyme Borreliosis: the European Perspective 10. Erythema Migrans 11. Cardiac Involvement 12. Rheumatological Involvement 13. Nervous System Involvement 14. Lyme Disease in Children 15. The Psychology of 'Post-Lyme Disease Syndrome' and 'Not Lyme' 16. Chronic Lyme Disease 17. Lyme Disease: the Great Controversy
Halperin was educated at MIT and Harvard and received his clinical training at the University of Chicago and Massachusetts General Hospital. Currently Professor of Neurology and Medicine at New York's Mount Sinai School of Medicine, he began his career on the neurology faculty of SUNY Stony Brook, just as Lyme disease was being characterized. The multidisciplinary collaborative group there was able to substantially improve the knowledge base regarding this infection. An author or contributor to approximately 150 articles and chapters, Dr. Halperin lectures widely. He serves on the Guideline Development Subcommittee of the American Academy of Neurology, has been a long-standing examiner for the Neurology Board examination, and has been heavily involved in patient outcome improvement at Atlantic Health, the multihospital system in New Jersey where he now leads Neurosciences. Under his leadership, Overlook Hospital's Neuroscience program has rapidly become recognized as the state's best and busiest.
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